10 Batch

Test Your Self In : Pharmacology

Tcells stimulate their own replication by
  1. IL-2
  2. IL-12
  3. IL-6
  4. IL-10
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Which of the following represents a host response to a bacterial infection designed to isolate the invading pathogens
  1. Pus formation
  2. Formation of a fibrin capsule
  3. Neutrophilic proliferation
  4. Cytokine release
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-------- is associated with adult T-cell leukaemia
  1. Human Rhinoviruses
  2. HTLV-1
  3. echoviruses
  4. coronaviruses
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Al of the followings are laboratory diagnostic targets of HIV except
  1. CD4 count
  2. Viral p24 antigen
  3. proviral DNA
  4. nigri bodies
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Al of the followings are the indirect mechanism of CD4 damage by HIV infection except
  1. Programmed cell death
  2. Loss of plasma membrane integrity by budding
  3. Autoimmune responses
  4. Syncytium formation
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All of the followings are the HIV criteria except
  1. Two RNA copies
  2. Infect mostly CD4 cells
  3. sialic acid receptor for attachments
  4. associated with opportunistic infections
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All of the followings are un conventional prion infection except:
  1. Kuru disease.
  2. Scrapie disease.
  3. Mad cow disease.
  4. HTLV1
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An infection with no detectable symptoms is called:
  1. fulminant
  2. latent
  3. subclinical
  4. secondary
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b cell dose not able to make antibodies without the aid of T-helper cell
  1. true
  2. false
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Bacterial endotoxin is poorly antigenic
  1. false
  2. true
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CCR5 &CXCR4 are the receptors of
  1. HIV
  2. HTLV
  3. HBV
  4. HSV
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Clonal selection, clonal activation and clonal replication are the sequence of lymphocytes activation
  1. true
  2. false
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Cytotoxic CD4T cells are able to recognize and bind virus infected body cells or tumor cells
  1. false
  2. true
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Diphtheria toxin damages tissue through
  1. Disrupting celular cytoplasmic membrane structure.
  2. Disabling the interaction of ribosomes with RNA during translation
  3. Damaging DNA structure.
  4. Prevent endoplasmic reticulum function
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How does the Diptheria toxin impede protein *?production ni atarget cells
  1. ADP ribosylation of adenylate cyclase
  2. ADP ribosylation of EF-2
  3. Inactivation of eEF-2 via an increase in CAMP
  4. Increase CAMP via adenylate cyclase activity
  5. Increase ADP which increases cAMP
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INF-p is produced mostly by
  1. Fibroblast
  2. Leucocytes
  3. CD4 TH1 cell
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major location of normal microbiota is
  1. Skin's stratum corner
  2. stomach
  3. external ear
  4. mouth
  5. gastrointestinal tract
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Many pathogenic bacteria obtain Iron by secreting:
  1. Iron-binding protein
  2. Ferritin
  3. Siderophores
  4. Transferrin
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medically important organism in humane nose is
  1. staphylococcus epidermidis
  2. staphylococcus aureus
  3. helicobacter pylori
  4. lactobacillus
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medically important organism of colon of breastfed baby only
  1. prevotella
  2. actinomycetes
  3. bactericides
  4. bifidobacterium
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Microglia is APC recognized by Tcells in the CNS
  1. true
  2. false
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most skin resident bacterial flora are located superficially in the dermis
  1. false
  2. true
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Neisserial endotoxin is referred to as lipooligosaccharide (LOS).
  1. true
  2. false
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number of shigella required to cause diarrhea is
  1. less then 100
  2. more than 100 000
  3. approximately 10000
  4. about 1000
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One of the following is not characteristic of NK cell
  1. play a role in ADCC
  2. Express antigen-specific receptors
  3. Recognizes carbohydrate ligands
  4. recognizes MHC class I molecules
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One of the following is not generate Memory cell:
  1. CD8 T cell
  2. CD4 T cell
  3. NK cell
  4. B cell
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organisms living together, sharing some nutrients but peacefully co-existing with neither coming to harm
  1. Commensalism
  2. mutualism
  3. symbiosis
  4. opportunistic
  5. parasitism
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Peptidoglycan is a major permeability barrier in Gram negative bacteria
  1. false
  2. true
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Regarding the main mechanism by which oncogenic DNA retroviruses, which one of the following is most accurate
  1. They cause point mutations in cellular regulatory genes.
  2. They carry the genes for proteins that act as cellular growth factors.
  3. They synthesize a protein that inhibits the action of the celular p53 protein
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the ------- was the first human Onco-retrovirus isolated from patient with cutaneous T-cell lymphoma
  1. HTLV-1
  2. HTLV-2
  3. HIV-1
  4. HIV-2
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the colon is the site of the largest number of normal flora bacteria, which on of the following bacteria is found in the greatest number in the colon
  1. clostridium perfringens
  2. escherichia coli
  3. enterococcus faecalis
  4. bactericides fragilis
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The component of lipopolysaccharide for Gram negative bacteria that si responsible for the effects of the toxin is
  1. lipid A
  2. peptidoglycan
  3. lipoprotein
  4. o side chain
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The Humoral immunity is based on
  1. activity of the NK cell
  2. activity of the B- lymphocytes
  3. activity of the -T lymphocytes
  4. activity of the interferon
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The infection with Treponema pallidum (syphilis) is
  1. latent
  2. secondary
  3. primary
  4. all of them
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The iron-binding protein ni liver is:
  1. Ferritin
  2. Transferrin
  3. Lactoferrin
  4. Hemoglobin
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The most characteristic feature of prodromal phase of HIV infection is the:
  1. sero-conversion
  2. latency period
  3. CD4 dropping
  4. flu-like form
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The pus of pyogenic inflammations contains mostly
  1. Fibroblasts
  2. Neutrophils
  3. Lymphocytes
  4. Macrophages
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True about capsule in bacterial cell:
  1. t Polysaccharide secreted by certain bacteria
  2. Unorganized and loosely attached to the cell wall
  3. it does not exclude particles of the dyes.
  4. important virulence factor by preventing phagocytosis
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which of the following is normal flora
  1. fungi
  2. viruses
  3. helmintes
  4. protozoa
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